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Ethylene thiourea (ETU) is an organosulfur compound with the formula C 3 H 6 N 2 S. It is an example of an N,N-disubstituted thiourea. It is a white solid. It is synthesized by treating ethylenediamine with carbon disulfide. Ethylene thioureas are an excellent accelerant of vulcanization of neoprene and polychloroprene rubbers. In commercial use is the N,N'-diphenylethylenethiourea.
The effect of ethylene thiourea (ETU) upon liver cells was evaluated in male Sprague-Dawley rats. ETU was administered ad libitum in drinking water at concentrations of 1, 5, 50, and 500 ppm for time intervals of 1, 2, and 5 days, 1 and 2 weeks, 1, 2, 4, and 8 months.
Effects of Ethylene Thiourea in Humans In addition to the negative effects in animal models, EDCs also have a host of negative effects in humans. Ethylene thiourea as a carcinogen and endocrine disruptor is well established in the literature and has been studied since the 1940s when it was determined to cause thyroid hyperplasia ( Seifter ...
96-45-7 - PDQAZBWRQCGBEV-UHFFFAOYSA-N - Ethylene thiourea - Similar structures search, synonyms, formulas, resource links, and other chemical information.
ETHYLENE THIOUREA may be sensitive to prolonged exposure to light. Incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. May react with acids to liberate hydrogen sulfide.
The rate of degradation of mancozeb and the residue dynamics of its primary metabolite ethylenethiourea (ETU) in table grapes is reported. Mancozeb residues dissipated following first order rate kinetics with a half-life of 15.4 and 18.2 days in the case of standard and double doses of 1.5 and 3 kg a.i/ha, respectively, when applied 4 times before harvest.
In some cases, the symptoms were severe. Patch testing was performed in 10 individuals and all reacted positively to the heat retainer and/or the rubber glue used in the heat retainer. A series of rubber chemicals was patch tested in 7 patients and all showed positive reactions to diphenylthiourea (DPTU), and all but one to ethylene thiourea (ETU).
In addition, ethylene thiourea can cause myxedema (the drying and thickening of skin, together with a slowing down of physical and mental activity), goiter, and other effects related to decreased output of thyroid hormone.
Ethylene thiourea is metabolized in the mouse liver, one of the target organs for the carcinogenicity of the substance, mainly by the flavin-dependent monooxygenase (FMO), to form a reactive, protein-binding product (see Section 2). Activation via this metabolic pathway, which may play a role in the genotoxic effects of ethylene thiourea (Hui ...
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NA-22 NA.22.D Pennac CRA Rhodanin S62 Robac 22 Sanceller 22 Sodium-22 Neoprene accelerator Vulkacit NPV/C Warecure C are trade names. Toxicity Information for Ethylene thiourea Note : Information for many chemicals is incomplete and may not be fully representative of effects on humans.
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Ethylene thiourea (ETU); CASRN 96-45-7 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data, as outlined in the . IRIS assessment development process. Sections I (Health Hazard Assessments for Noncarcinogenic Effects) and
Graham SL, Hansen WH: The effects of short-term administration of ethylene thiourea upon thyroid function in the rat. Bull Environ Contam Toxicol 7(1):19-25, 1972 Graham SL, Hansen WH, Davis KJ, Perry CH: Effects of one-year administration of ethylenethiourea upon the thyroid of the rat.
Ethylene Thiourea ETU(NA-22) Vulkacit CAS NO. 96-45-7 Application The product can be used for chloroprene rubber, Epichlorohydrin rubber, chlorinated polyethylene, etc., are particularly suited for non-curing system of the chlorine-butylamine Hopewell accelerator. can form the best rapid vulvanization with the right selection system during 100-500*C, and the whole parade security.
Dalvi RR, Dalvi PS. Differences in the effects of piperine and piperonyl butoxide on hepatic drug-metabolizing enzyme system in rats. Drug Chem Toxicol. 1991; 14 (1-2):219–229. Freudenthal RI, Kerchner G, Persing R, Baron RL. Dietary subacute toxicity of ethylene thiourea in the laboratory rat. J Environ Pathol Toxicol.
Ethylene thiourea has been measured in food products, where it is believed to be a metabolite of EBDC fungicides (Houeto et al. 1995). Ethylene thiourea was found in beer at concentrations of 0.026 to 0.07 ppm and in wine at 0.037 ppm. The U.S. Food and Drug Ad-ministration's Total Diet Study found ethylene thiourea in 27 differ-
Ethylene thiourea is believed to induce thyroid tumors through the suppression of thyroxine syntheses, leading to hyperplasia of the thyroid gland. Ethylene thiourea was a potent teratogen in rats at doses that produced no maternal toxicity or fetal deaths.
For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Ethylene Thiourea is a white to pale green crystalline (sand-like) solid, with a faint Amine odor. It is used in electroplating, insecticides, fungicides, dyes, pharmaceuticals, and synthetic resins, and in making Neoprene rubber. REASON FOR CITATION * Ethylene Thiourea is on the Hazardous Substance List because it is cited by NIOSH, NTP, DEP ...
ethylene thiourea (ETU), a commonly used endocrine disrupter, to alter thyroid function during pregnancy affecting fetal development. Normal Physiology of the Fetus, Thyroid Gland, and Endocrine Function The thyroid gland is responsible for mediating a number of normal physiological changes during pregnancy and is a
Imidazoline-2-thione UNII:24FOJ4N18S 1,3-ethylene-2-thiourea 1,3-Ethylenethiourea 12261-94-8 [RN] 13966-32-0 [RN] 2 Mercaptoimidazoline 26856-29-1 [RN] 2H-Imidazole-2-thione, tetrahydro- 2-Imidazolidimethione 2-imidazolidinethione 97% 2-imidazolidinethione, 98% 2-imidazolidinethione, paraffinic oil coated powder,...
'All three have been shown to be active in a variety of yeast-based screens and there is some evidence that urethane and thiourea may induce free radicals in yeast cells.' 'Though the mutagenic activity of ethylene thiourea is well documented, very little is known about the deleterious effects of zineb.'
Ethylene thiourea (ETU) is a metabolite and an environmental degradation product common to several fungicides classified as ethylene bisdithiocarbamates (EBDCs), which are formulated either as zinc or manganese salts (zineb, maneb), or as polymeric metal-coordinated complexes (metiram, mancozeb).
Ethylene Thiourea C3h6n2s Vulkacit Etu(na-22), Find Complete Details about Ethylene Thiourea C3h6n2s Vulkacit Etu(na-22),Vulkacit Etu(na-22),C3h6n2s,Ethylene Thiourea from Rubber Auxiliary Agents Supplier or Manufacturer-Henan GO Biotech Co., Ltd.
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This IRIS assessment for Ethylene thiourea (ETU) consists of hazard identification and dose-response assessment data and provides support for EPA risk management decisions.
Ethylene thiourea is used in the rubber industry and in the production of some fungicides. No information is available on the acute (short-term) or chronic (long-term) effects of ethylene thiourea in humans. In rodents chronically exposed to ethylene thiourea in their diet, effects on the thyroid have been observed.
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